Photobiomodulation, or PBM, is the science of using specific wavelengths of light to improve human health.
What is Photobiomodulation?
Photobiomodulation (PBM) describes the therapeutic use of red and near-infrared light to stimulate healing, relieve pain and inflammation, and improve overall wellness.
When delivered at the correct frequency and location for an optimal duration of time, infrared light produces a photochemical reaction that increases ATP and improves cellular function and health. We believe this photosynthetic process is crucial for the health and wellness of the
The Benefits of PBM
Photobiomodulation provides many benefits to human health, including improved cognitive ability, sleep optimization, pain management, muscle recovery, and much more.
Just as hydration is important for the body, proper photobiomodulation is integral to a healthy life. The science proves it, and those who integrate PBM into their lifestyle notice the difference.
Health care that powers and heals your cells shouldn’t be tucked away in a clinic. So at JustLight, we’re bringing this life-giving photochemical process to your home by making photobiomodulation effective, accessible and affordable.
The History of PBM
PBM dates back as far as the ancient Romans, who used light from the sun to heal. More recently, in 1903, a scientist named Niels Finsen won the Nobel Prize for curing lupus vulgaris and smallpox with light!
Since then, NASA has used red light in space to help plants grow and astronauts heal. Today, we are living in the most revolutionary period of photomedical history: photobiomodulation at home.
The Science Behind Photobiomodulation
Photobiomodulation (PBM) also known as low-level laser therapy is the use of red and near-infrared light to stimulate healing, relieve pain, and reduce inflammation. The primary chromophores have been identified as cytochrome c oxidase in mitochondria and calcium ion channels (possibly mediated by opsins during light absorption). Secondary effects of photon absorption include increased ATP, a burst of reactive oxygen species, an increase in nitric oxide, and modulation of calcium levels. Tertiary effects include activation of a wide range of transcription factors leading to improved cell survival, increased proliferation and migration, and new protein synthesis.
Light causes a pronounced biphasic dose response whereby low levels of light have stimulating effects, while high levels of light have inhibitory effects. It has been found that PBM can produce ROS in normal cells, but when used in oxidatively stressed cells or in animal models of disease, ROS levels are lowered. PBM is able to upregulate antioxidant defenses and reduce oxidative stress. It was shown that PBM can activate NF-kB in normal quiescent cells. However, in activated inflammatory cells, inflammatory markers were decreased. One of the most reproducible effects of PBM is an overall reduction in inflammation, which is particularly important for disorders of the joints, traumatic injuries, lung disorders, and the brain. PBM has been shown to reduce markers of M1 phenotype in activated macrophages. Many reports have shown reductions in reactive nitrogen species and prostaglandins in various animal models. PBM can reduce inflammation in the brain, abdominal fat, wounds, lungs, and spinal cord.
Why have most people never heard of PBM?
Until recent years, photobiomodulation was largely available only to clinics, hospitals, and the wealthy. In the past decade, however, LED (light-emitting diode) technology has swiftly become more affordable, compact, and powerful, resulting in new use cases and increased access for the general public.
Additionally, PBM was first associated with, and subsequently relegated to, the fitness and beauty industries. While PBM does serve an important cosmetic role, its proven ability to effectively treat and prevent countless diseases (including Alzheimer's, cancers, depression, and more) is so much more important. As the number of positive clinical studies and the accessibility to LEDs increase, PBM is poised to revolutionize the healthcare industry within the next two years. Thanks to the increasing availability of red and near-infrared LEDs, PBM is becoming a recognized therapeutic practice by doctors, physical therapists, and the general public.
PBM and Alzheimer's
Photobiomodulation supports recovery from brain injury and reversal of cognitive decline through dozens of positive photochemical reactions.
Healing mechanisms include increased blood flow and energy production, reduced inflammation, and the genesis of new cells. These processes take place when photons are absorbed in the mitochondria (cytochrome c oxidase) and ion channels of cells, triggering the activation of signaling pathways, upregulation of transcription factors, and increased expression of protective genes.